Unable to open TaskMgr, MsConfig, CMD, and regedit

Hi All,

I am unable to open the Task Manager, RegEdit, MsConfig and Command Prompt (from anyways) in my laptop.

I am able to open all of them in safe mode, but they are not opening in normal mode.

Please guide.

1) Are you the local admin when attempting? If so, I bet a worm has borked with your LSA settings.
2) Have you checked the registry for signs of pwnag3 when you're in safe mode?
Typically this behavoir is related to an infection. I know for sure that W32/Rbot-ANK causes this.

Go into safe mode and tell me the contents of this hive:
HKLM\SOFTWARE\Microsoft\Windows\CurrentVersion\Run

--TH13

Or, are you on a company/school etc network with restrictions applied?