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Are there any backdors in the program others could use?
Since you are sharing files, obviously there is always the possibility that some of the files could contain Trojans, Viruses, etc. Make sure you always scan your downloaded files with a reputable virus scanner and use common sense concerning the files you download. I should caution you that Shareaza is a peer-to-peer client, however when it is downloaded from a reputable site, it most likely will not contain any Trojans, viruses, spyware, etc.