if you want to remove virus from your computers, i recomend this steps.

1) download sysclean and the lattest pattern file from trendmicro

2) Shutdown your network.

3) Shutdown the system Restore (if you have) then reboot the computers and enter in safe mode

4) run the sysclean in your computers

5) ask your sys admin for a Anti-virus server + client

If your working in a small company, you can try Avast Pro.
and at home you can use Avast Home (its free).

This is a quite good anti-virus, and its free for home users.