I've used several different vendors of antivirus software over the course of a few years: McAfee, Symantec, Trend Micro, Panda, AVG...none of these of impressed me as far as detection of known threats, detection of unknown threats, etc. goes. Additionally, a few of them are quite the resource hog and dramatically slow performance on my machines whether scanning or not.

I browsed around the forums and around the internet and it seems as if NOD32 receives some very good reviews, as does BitDefender (first time I've heard of them).

Can anyone provide a recommendation for decent antivirus software that isn't a resource hog and has very good detection and protection?