What if every security measure fails...

[dredogol]

This is just a "what-if" scenario, and I really doubt there are many virus/trojan/malware/rootkit/etc capable of doing this:

**Assume a Wired connection w/ default ISP router/modem
**Assume using OpenDNS and a 3rd party Proxy service

1) Bypass web browser securities - (IE. Firefox w/ NoScript, AdBlock, BetterPrivacy, BlackSheep, HTTPS-Everywhere, etc.)
2) Bypass sandboxed browser - (IE. Sandboxie)
3) Bypass AV/ISS with IDPS
4) Bypass auto-exec programs - (IE. Faronics Anti-Executable)
5) Bypass sandboxed VM - (IE. DeepFreeze, RSS/RVS, etc)
6) Infect the locked OS files

That's basically my setup plan for my new system... but I really doubt there are that many malware capable of getting through all that (from a clicky-clicky / Adobe / Flash infection).

Anything else I should add to better protect myself and prevent all of the above from failing?
I know nothing is 100% hack-proof due to exploits, but I'm trying to learn to see what options I have available (that is all/mostly Free)...