<shameless plug>
You could always use ProcMail! You too could have squeaky clean email free from the dingy, scum buildup of spam.
</shameless plug>

Blacklists are unfortunately a necessary evil in the war against spam, but they do offer some benefits. When you are 'blacklisted' as an ISP, you are generally provided notice (even if you aren't, you can generally find out that your mail is going into a black hole from the logs). Frequently, you have the option of contacting the owner of the list and asking why you were blacklisted. They will usually be able to provide you with some documentation, and from there you can seek out the evil spammer on your own network or setup some outgoing mail filters to catch it if they try it again. This is often enough to get you removed from the blacklist, and you are again in good standing with the internet community.

I look at getting blacklisted like getting a parking ticket. If you get blacklisted, you know you should have been more careful about monitoring your outgoing email (like blocking relaying, monitoring load spikes on your mailserver, etc), and getting blacklisted is an unfriendly reminder to pay more attention in the future. Most ISPs will do anything they can to get off the blacklist and return to good standing, so I don't forsee spam bringing email to a grinding halt. It's just one of those nuisances we all have to learn to deal with.