Hi,

http://www.runtimeware.com

"Sentinel" is a reasonable integrity checker

http://digilander.libero.it/zancart

"Winsonar" checks for new processes launching in the background, and can be set to prevent new executables being launched when you have an internet connection open.

http://www.winpatrol.com
http://www.diamondcs.co.au (RegistryProt)

If you haven't already got them


Every little helps?

EDIT: http://www.f-secure.com/v-descs/magistr.shtml

I know it is three years old, but was along the same lines as what is being discussed here?