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25 is simple mail transfer, 110 is pop (post office protocol), and 135 is DCE endpoint resolution. All of these have to do with email,
Actually, RPC is used for e-mail in MS Exchange environments only but it also has a much more common use. The RPC Endpoint Mapper process is responsible for maintaining the connection information for all of the processes on that machine using RPC. The Endpoint Mapper process runs within the RPC service itself which provides inter-process communication mechanism that allows a program running on one computer to seamlessly execute code on a remote system.