Help Desk Software - Is It Secure

I am working on my SANS-GSEC certification. My paper topic is that Problem Tracking Software is great for help desks, but not well designed for use in the security area. Ex: Patient Health Information, SSNs, incident response, inappropriate web use, etc. Anyone have other items that would be considered sensitive that you would not put into problem tracking software?

~Nimh

Phone Numbers, Last names, addresses....things like these could be used against people. For example they could be used to stalk a person.

Payroll
Personnel Data
Trading/Dealing Data (Stocks, Bonds, Currency, Commodities)
Anything classified under national security regulations
Anything containing credit card information

Just a few thoughts :)