Well, according to the advisory on http://www.cert.org/advisories/CA-2002-17.html, it can lead to a compromise of content as well as to a denial of service condition. It also specifically mentions that UNIX versions of apache are vulnerable as well.
Furthermore, it also mentions that the patch supplied by ISS is geared towards WIN32 Apache and will not fix the UNIX versions and that is generally a bad idea to apply the patch.
