Do you have to run every MS Patch or just the Latest?

"I didn't want to start a new thread for this question, but there were way too many posts with the keywords i searched for."

Thanx Guys/Gals :-)

<edit>
Alright guys/gals- i was looking on "http://microsoft.com/technet/" and found the answer to my question.

Some do, some don't.

According to Microsoft some patches will include the functionality of all previously patches. And others are more specific as to what they will take care of.</edit>