Definatly delete anything SpyBot finds, only things that may stop working are applications that have adware in them like kazza and such. You may want to check your registry's Run and Run Services (if win98) to see what is starting on boot found at: HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Windows\Current Version\ and in HKEY_CURRENT_USER\SOFTWARE\Microsoft\Windows\Current Version\. Also check your Startup folder under the start menu both for the current user and All Users. Research any wierd files you may have in these places.