I am planning to use Nessus (installed on Desktop) at work (production devices)

1- Is there any difference between Nusse Linux platform and Windows Platform ?
2- Is it a good idea to use more than one monitoring tools on different PCs, like Nusses on one PC and SolarWinds on other PC or ?
3- Does using Nusses (Linux or windows) affect any network devices (Cisco devices, hp servers, etc )
4- Is it necessary the PC which has got Nessus installed on it, to join AD domain ?