Those blank error boxes are the worst kind of all.

Here are a few quick suggestions off the top of my head.
1. If you’re running xp you could always try a role back
2. Update your virus scanner and scan for virus
3. If it is a cracked version that might be your problem. Some game hacks can do some pretty funky stuff to your computer.
4. Some error messages you just can't fix so a reinstall of the os would be a poor mans fix if you’re stumped.
5. Make sure there’s no spy ware on your computer sometimes the hidden programs running in the back ground can conflict with other programs. Download Ad-aware, it will take care of most spy ware.