Personally I think that 'serious' computer user keyboards won't focus on tiny footprints, but on the easy spacing of keys. After all, ease of use is paramount if you use it a lot, not footprint. I'm not ashamed to say that I love my (original version) Microsoft Natural keyboard. I really dislike keyboards which bunch together the arrow keys and the Ins/Del/Home/etc. keys along with the printscreen/scroll-lock/etc. block in order to fit in the frivolous sleep/wake buttons.

I'd agree with Deb. When I first started my ickle widdle footsies on the path to typing, I thought the number pad was a frivolous addition to a keyboard, but since then I've found it invaluable for entering numeric strings of all types, to say nothing of using it with Calculator-like programs. My keyboard qualitfies as a big-clunker, but the extra space really helps me navigate it blindly, rather than hampering me by requiring extra movement.