like dead said, you cant do it...i wanted to do it a while back. anyways, what i did is i just got Outpost firewall and i told it to block Internet Explorer. Then i got POW and whenever the IE window had the title "Page cannot be found" or whatever it is, it would automatically close IE. Anyways, i have never got another pop-up since I was told to delete all the shortcuts to IE and that might help out a little bit, but if i were you i wouldnt delete all the shortcuts because sometimes, IE is the only browser that will work