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September 28th, 2003, 07:22 PM
#61
H3R35 MY 7RIBU73 70 MI55 MITT3N5.
Msmittens, i am writing this Tutorial about you, as i wanna be like you.
Here are my reason's why i wanna be like you.
1:You are a wannabe Professor who teaches invisible students at her invinsible college
2:You claim to be smarter then what you really are.
3:You have no social life, as your always in here AO
4:The only time you leave the omputer, is when you either go to get more donuts.
Or when you go and smother your **** with dog food and let your k-9 friend lick it of..
5:You tell me not to plageris?
Well to that i say the following.
You should know all about p[lagarism huh?
You got permission from Trey P{arker to use Cartman as your Avator?
I think not.
You too have posted some tutorials here that weren't yours. And yet others seem to think that 's fine, but when some n00bie walks in and posts a tutorialm, that kills all the tutorials that you've ever made in one hit.
You crack the ****'s and get your other lam0r friends to neg me.
And like negging really offends me, infact it makes me wanna post more and more and more until you can take no more of this.
MsMittens this ain't gonna end.
You gonna have to try and block me from reentering this place, if you ever wannna stop me from attacking your character.
Im not gonna stop and your never gonna stop being a fake so im nearly like you.
And so in closing you all can rant and rave and insult me, but hey like i care less.?
????????//????????????????
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September 28th, 2003, 07:56 PM
#62
Bleh Kazaa Bleh More crap about Kazaa bleh bla bleh!
Jeeebus, theres a search function on this board and enough posts about Kazaa to derive it's source code! God I'm sick and tired of these threads!
With all the subtlety of an artillery barrage / Follow blindly, for the true path is sketchy at best. .: Bring OS X to x86!:.
Og ingen kan minnast dei linne drag i dronningas andlet den fagre dag Då landet her kvilte i heilag fred og alle hadde kjærleik å elske med.
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September 28th, 2003, 09:17 PM
#63
Originally posted here by Noia
Bleh Kazaa Bleh More crap about Kazaa bleh bla bleh!
Jeeebus, theres a search function on this board and enough posts about Kazaa to derive it's source code! God I'm sick and tired of these threads!
Easy to say when your favorite music didn't take a bashing.
In my posts i'm not talking about some obscure drugged out junkies scream'n garbage down a mic (punk crap) i am talking about popular music that you can at least understand the lyrics to. So go dye your hair black, put on some black nail-polish, get some black doc-martins and some **** stuck into your face and scream the house down dumb ass.
It\'s 106 miles to Chicago, we\'ve got a full tank of gas, half a pack of cigarettes, it\'s dark and we\'re wearing sunglasses.
Hit it!
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September 29th, 2003, 01:36 AM
#64

100 posts yeeeehaaaa at least i got a tonne before getting banned
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September 29th, 2003, 03:34 AM
#65
The RIAA is the only company out there that's mass-suing its customer base. They went after at 12 year old girl and her parents now have been sued and are paying the RIAA $2000 bucks for "retribution". There are countless other cases involved and can be found on the net.
Do I think file-sharing is illegal? Well, let's see. Do I see Adobe or any other major company that makes mega software suing people who download their software "illegally"? No. Do you see MS going after people with illegal copies of 2K or XP? No. I'm talking more than one specific case. They don't exist because these companies don't do it. The RIAA is completely different. They've been ripping people off for the past 15 years almost and only now are they actively trying to lower prices on CDs, something they are quoted to have done 10 years ago "after manufacturing ramps up for the new CD process".
On one hand, I listen to Bon Jovi's "It's my life" song and I like it so I go to the store and by the $24.99 CD. 19 songs and with exception of that one song I liked, the rest were COMPLETE SH!T, being produced by the same "producer" that did Brittany Spears last CD. Boy was I pissed off at that waste of money that gave Bon Jovi and his band around 2.00 and the RIAA gets the rest. Yeah, who benefits there?
On the other hand, I download and listen to two songs by Kelly Clarkson (from Kazaa). I like them both so I go buy the CD. Imagine my surprise when my 20 buck CD was mostly good and I liked most of the songs (more than 5). That's what I'm talking about and that's where the "evil system" proves those that think filesharing is wrong. Illegal is only defined by those who think it's wrong. If I can use a system that would show me what's good and what's bad, I'll use it because I do not want to give away my hard-earned cash to buy something that's an overnight success with no longevity and hear said company (RIAA) laughing all the way to the bank.
That's why the RIAA doesn't like it. If people had that choice, to buy what they wanted and nothing else, most of the bands out there wouldn't live past a week because of all the mainstream crap that's considered music turns out to be the only decent song they have on a CD that has 15+ more crap-tastic songs on it.
We the willing, led by the unknowing, have been doing the impossible for the ungrateful. We have done so much with so little for so long that we are now qualified to do just about anything with almost nothing.
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September 29th, 2003, 04:34 AM
#66
Didn't the U.S. government send in the swat team or similar to take into custody some poor little Cuban kid, with guns and masks the whole action movie look?
Just an example of the way of thinking in that country, and you look down at other nations society, judging them on their ways, have a look in the mirror.
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September 29th, 2003, 04:47 AM
#67
No one said **** about how any country did anything? Are you trying to be relevent again? Heh, the US has some stupid laws. Highest crime rate, yet were the toughest on drug laws....
Oh yea, because you cant actually blame crime on drugs. I challenge every member here to argue that one with me, I have yet to loose. No one would get shot over drug deals of they were legal. No one would get hurt for drug money, if it was legal to grow your own.
Hmmmm, thats usually what people say to you when you say "ok lets argue". But that **** dont work on me, Im smarter than that. I know the stats.
Oh yea, as for driving....Did you know that more than half the people they tested in those crashes were also drunk? You wont see that in no damn truth commercial. Because they dont wanna admit that it really isnt as bad as they say.
Im not saying lets legalize everything, I am saying legalize pot and Opium though. The good side effects are huge. And they are used as meds all the time without people realising it. I think the only thing you could say is "Well Opium is addictive". Heh, so is oxygen, go without that for a few and see how you do.
Also, people who drive while trashed....They shouldnt. That aint right, but those of us who sit at home and relax...We are NOT ****ing criminals. Howabout the police do something worth while? Go beat a rapist with your stupid club, leave us alone. Anyway, Im kinda tired, but this thread went to **** anyway, so I'm turning it around. It's already an arguement, so I'm just adding my choice of words to its fuel.
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September 29th, 2003, 05:33 AM
#68
TidaLphasE23 that kid was being held by an armed group of refugees that refused to let him be returned to the custody of his father.They defied a federal court order and promised to fight to keep him. what would the AU gov do....send in the girl scouts?
Bukhari:V3B48N826 “The Prophet said, ‘Isn’t the witness of a woman equal to half of that of a man?’ The women said, ‘Yes.’ He said, ‘This is because of the deficiency of a woman’s mind.’”
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September 29th, 2003, 06:00 AM
#69
Originally posted here by gore
I challenge every member here to argue that one with me, I have yet to loose.
Today's your lucky day. Ill give you something to post your 1000th on. 
Oh yea, because you cant actually blame crime on drugs.
Its time for a history lesson:
In the past, The Netherlands has been a country virtually free from crime, I think we can all agree. In the past decades, however, drug-related crimes have shot up several hundred percantages.
The big drug problem in Europe, especially in The Netherlands, started after the United States withdrew from Vietnam. Much of the heroin from the “Golden Triangle” (Laos, Thailand, Burma)went to Vietnam during the time that some 800,000 United States soldiers were stationed there. After the Americans withdrew, Chinese syndicates in Hong Kong and Bangkok lost their lucrative market in Vietnam and did everything possible to build up a market in Europe. To this day, they largely used their contacts with criminal elements among the Chinese in The Netherlands.
Now look at the Netherlands today. The Dutch society is riddles with juvenille delinquency, theft, murder, the whole gamut. If someone is robbed or assaulted in public, no one lifts a finger to provide help. Obviously, then, the great increase in crime is directly related to drugs.
Throughout The Netherlands, especially in the city of Amsterdam, crime is greatly on the rise. Addicts, unable to pay the steep black-market price for drugs, are resorting to theft. They are even breaking into pharmacies to hunt for opium and morphine.
OK, I think that sums up my first argument, ill give you a chance to rebutt. The ball is in your court, gore.
It\'s 106 miles to Chicago, we\'ve got a full tank of gas, half a pack of cigarettes, it\'s dark and we\'re wearing sunglasses.
Hit it!
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September 29th, 2003, 06:13 AM
#70
Heh, my 1000th post, lol.
How are they on drug laws? I have never been there in my life, I do know that the US is way more strict on drug laws than any country in the world and we also have the largest crime rate. Also, Heroin is one of those things I wouldnt legalize. Well, I would because it would help fight aids, no one needs to share needles if they can get them.
Also, kids being dick heads isnt directly related to drugs, that is parents being lazy. I'm not saying beat your kids, but if they do things that are horrid, let them know about it. I dont think its wrong to hit a kid when they have done wrong, but by hit I dont mean punch, I mean spanking. Also, for this to work, people would have to *GASP* be Responcible!!!!!!! =O
I know its a shocking thought, but blaming everything but yourself rarely is the right thing. Me, Yea Iv done drugs, I still like pills, and I want some opium, but do I commit crimes? No, Well not life threatening ones anyway heh.
How exactly are you saying drugs are hurting this country though? Most people in the US say people murder for drug money, well to me they wouldnt need to because pot and opium can be grown home grown from a plant and you wouldnt need money for it.
Heroin, yes its 100% natural (purified Morphine with aspirin added in is how you make it) but its way to addictive and feels to good, so I wont do it. Evem I draw the line somewhere. I dont know much about that country but it would be hard to prve drugs are directly related to crime if they are actually completly legal.
I mean you have to know that when you grow the plants yourself it doesnt cost anything more than water to make them grow. Both pot and Opium dont need anything special to get a useable drug out of. Pot you use the buds, Opium, you slice the pods before they bloom and let the sap drip out and sit, after a bit it turns brown/black and you pull it off and smoke it.
Also, the medical world has MANY uses for both. Almost every pain killer used in hospitols is made from opium. Also most cough suppressents are ade from opium, it stops you from coughing, cures the shits, and also puts you in a good mood, takes away depression, and also gives you a warm feeling.
Some FACTS about Opium you'll never see on an Anti drug site:
Homer conveys its effects in The Odyssey. In one episode, Telemachus is depressed after failing to find his father Odysseus. But then Helen...
"...had a happy thought. Into the bowl in which their wine was mixed, she slipped a drug that had the power of robbing grief and anger of their sting and banishing all painful memories. No one who swallowed this dissolved in their wine could shed a single tear that day, even for the death of his mother or father, or if they put his brother or his own son to the sword and he were there to see it done..."
In some parts of the contemporary Middle East, chilled glasses of poppy tea are served to mourners at funerals to ease their grief.
Papaver somniferum has long been popular in Europe. Fossil remains of poppy-seed cake and poppy-pods have been found in Neolithic Swiss lake-dwellings dating from over 4,000 years ago. Poppy images appear in Egyptian pictography and Roman sculpture. Representations of the Greek and Roman Gods of sleep, Hypnos and Somnos, show them wearing or carrying poppies.
Throughout Egyptian civilization, priest-physicians promoted the household use of opium preparations. Such remedies were called "thebacium" after the highly potent poppies grown near the capital city of Thebes.
Egyptian pharaohs were entombed with opium artifacts by their side. Opium could also readily be bought on the street-markets of Rome. By the eighth century AD, opium use had spread to Arabia, India and China. The Arabs both used opium and organized its trade. For the Prophet had prohibited the use of alcohol, not hashish or opiates.
Classical Greek physicians either ground the whole plant or used opium extract. Galen lists its medical indications, noting how opium...
"...resists poison and venomous bites, cures chronic headache, vertigo, deafness, epilepsy, apoplexy, dimness of sight, loss of voice, asthma, coughs of all kinds, spitting of blood, tightness of breath, colic, the lilac poison, jaundice, hardness of the spleen stone, urinary complaints, fever, dropsies, leprosies, the trouble to which women are subject, melancholy and all pestilences."
Later authorities were scarcely less enthusiastic. Physicians commonly believed that the poppy plant was of divine origin; opium was variously called the Sacred Anchor Of Life, Milk Of Paradise, the Hand Of God, and Destroyer Of Grief. Thomas Sydenham, the 17th-century pioneer of English medicine, writes....
"Among the remedies which it has pleased Almighty God to give to man to relieve his sufferings, none is so universal and so efficacious as opium."
This may be overstating God's benevolence; but by relieving emotional as well as physical pain, opiates have been understandably popular. Robert Burton, scholar, priest and author of Anatomy of Melancholy, commended laudanum - essentially opium dissolved in wine - for those who were insomniacs...
"...by reason of their continual cares, fears, sorrows, dry brains [which] is a symptom that much crucifies melancholy men..."
Indeed opium was probably the world's first authentic antidepressant. Unlike other pain-relieving agents such as ethyl alcohol, ether or the barbiturates, opium doesn't impair sensory perception, the intellect or motor co-ordination.
Pain ceases to be threatening, intrusive and distressing; but it can still be sensed and avoided. At lower dosages, opium may be pleasantly stimulating rather than soporific. In the East, opium was typically treated as a social drug; and opium-smoking was a tool for conviviality.
Nowadays a life of habitual opioid use evokes images of stupor and mindless oblivion, yet ironically Coleridge coined the word intensify to describe opium's effects on consciousness.
By the nineteenth century, vials of laudanum and raw opium were freely available at any English pharmacy or grocery store. One nineteenth-century author declared: "[Laudanum] Drops, you are darling! If I love nothing else, I love you." Another user, the English gentleman quoted in Jim Hogshire's Opium for the Masses (1994), enthused that opium felt akin to a gentle and constant orgasm.
Youngsters were introduced to the pleasures of opiates at their mothers' breast. Harassed baby-minders - and overworked parents - found opium-based preparations were a dependable way to keep their kids happy and docile; this was an era before Ritalin. Sales of Godfrey's Cordial, a soothing syrup of opium tincture effective against colic, were prodigious.
But Godfrey's Cordial had its competitors: Street's Infants' Quietness, Atkinson's Infants' Preservative, and Mrs. Winslow's Soothing Syrup.
Opium was viewed as a medicine, not a drug of abuse. Contemporary medical theory didn't allow that one could become addicted to a cure. However, the chemists and physicians most actively investigating the properties of opium were also its dedicated consumers; and this may conceivably have coloured their judgement.
Writers of distinction certainly consumed opium in copious quantities. Samuel Taylor Coleridge (1772-1834) wrote Kubla Khan in a dream-like trance while under its spell; opium promotes vivid dreams and rich visual imagery as well as gentle euphoria...
"In Xanadu did Kubla Khan
A stately pleasure-dome decree
Where Alph, the sacred river, ran
Down to a sunless sea
...
I would build that dome in air,
That sunny dome, those caves of ice!
And all who heard should see them there,
And all should cry, Beware! Beware!
His flashing eyes, his floating hair!
Weave a circle round him thrice,
And close your eyes with holy dread,
For he on honey-dew hath fed,
And drunk the milk of Paradise."
Fellow English author Thomas de Quincey (1785-1859) writes of "the marvelous agency of opium, whether for pleasure or for pain". De Quincey seems to have treated opium as a mood-brightening smart-drug. The author of Confessions of an English Opium-Eater (1821) draws invidious comparisons with alcohol. He attributes a heightening of his mental powers to opium use...
"Whereas wine disorders the mental faculties, opium introduces amongst them the most exquisite order, legislation and harmony. Wine robs a man of self-possession; opium greatly invigorates it....Wine constantly leads a man to the brink of absurdity and extravagance; and, beyond a certain point, it is sure to volatilize and disperse the intellectual energies; whereas opium seems to compose what has been agitated, and to concentrate what had been distracted. ...A man who is inebriated...is often...brutal; but the opium eater...feels that the diviner part of his nature is paramount; that is, the moral affections are in a state of cloudless serenity; and over all is the great light of majestic intellect...."
De Quincey states that not he himself, but opium, should be regarded as the true hero of his essay. Opium was his "Divine Poppy-juice, as indispensable as breathing". By reputation, opium users have dull wits, idle lives and diminished sensibility. This was not de Quincey's verdict. He made a habit of going to the opera under its influence - and found his experience of music delightfully enhanced...
"Now opium, by greatly increasing the activity of the mind, generally increases, of necessity, that particular mode of its activity by which we are able to construct out of the raw material of organic sound an elaborate intellectual pleasure...It is sufficient to say, that a chorus, etc of elaborate harmony displayed before me, as in a piece of arras work, the whole of my past life - not as if recalled by an act of memory, but as if present and incarnated in the music; no longer painful to dwell upon, but the detail of its incidents removed...and its passions exalted, spiritualized, and sublimed..."
Opium induces gentle, subtle, dream-like hallucinations very different from the fierce and unpredictable weirdness of LSD. Baudelaire (1821-67) likens opium to a woman friend, "...an old and terrible friend, and, alas! like them all, full of caresses and deceptions."
Across the Atlantic, in 1842, William Blair describes his experiences with opium in a New York magazine...
"While I was sitting at tea, I felt a strange sensation, totally unlike any thing I had ever felt before; a gradual creeping thrill, which in a few minutes occupied every part of my body, lulling to sleep the before-mentioned racking pain, producing a pleasing glow from head to foot, and inducing a sensation of dreamy exhilaration (if the phrase be intelligible to others as it is to me) similar in nature but not in degree to the drowsiness caused by wine, though not inclining me to sleep; in fact far from it, that I longed to engage in some active exercise; to sing, dance, or leap...so vividly did I feel my vitality - for in this state of delicious exhilaration even mere excitement seemed absolute Elysium - that I could not resist the tendency to break out in the strangest vagaries, until my companions thought me deranged...After I had been seated [at the play I was attending] a few minutes, the nature of the excitement changed, and a 'waking sleep' succeeded. The actors on the stage vanished; the stage itself lost its reality; and before my entranced sight magnificent halls stretched out in endless succession with galley above gallery, while the roof was blazing with gems, like stars whose rays alone illumined the whole building, which was tinged with strange, gigantic figures, like the wild possessors of lost globe...I will not attempt farther to describe the magnificent vision which a little pill of 'brown gum' had conjured up from the realm of ideal being. No words that I can command would do justice to its Titanian splendour and immensity..."
In North America, the initial history of Papaver somniferum was somewhat more peaceful. During the first few centuries of European settlement, opium poppies were widely cultivated. Early settlers dissolved the resin in whisky to relieve coughs, aches and pains.
The plant had further uses. Papaver somniferum produces lots of small black seeds. Poppy-seeds are an ingredient of typical bird-seed and a common garnish on rolls. Poppy-seeds can also be ground into flour; used in salad-dressings; added to sauces as flavoring or thickening-agents; and the oil can be expressed and used in cooking. Poppy-heads are infused to make a traditional sedative drink.
Many distinguished early Americans grew Papaver somniferum. Rightly or wrongly, they would today be treated as felons. Thomas Jefferson cultivated opium poppies at his garden in Monticello. The seeds from its plants, including the poppies, were sold at the gift-shop of Thomas Jefferson Center for Historic Plants until 1991 - when a drug-bust at the nearby University of Virginia panicked the Board of Directors into ripping up the plants and burning the seeds. The cultivation of Papaver somniferum is banned in the USA under the Opium Poppy Control Act of 1942. Amateur horticulturists, however, continue to value the beautiful red, yellow and white flowers as adornments to their gardens.
Until the nineteenth century, the only opioids used medicinally or recreationally took the form of crude opium. Opium is a complex chemical cocktail containing sugars, proteins, fats, water, meconic acid, plant wax, latex, gums, ammonia, sulphuric and lactic acids, and numerous alkaloids, most notably morphine (10%-15%), codeine (1%-3%), noscapine (4%-8%), papaverine (1%-3%), and thebaine (1%-2%). All of the latter, apart from thebaine, are used medicinally as analgesics. The opioid analgesics are of inestimable value because they reduce or abolish pain without causing a loss of consciousness. They also relieve coughs, spasms, fevers and diarrhea.
Even thebaine, though without analgesic effect, is of immense pharmaceutical worth. This is because it can be used to produce semi-synthetic opioid morphine analogues such as oxycodone (Percodan), dihydromorphenone (Dilaudid), hydrocodone (Vicodin) and etorphine (Immobilon). Classes of morphine analogue include the diphenylpropylamines (e.g. methadone), the 4-phenylpiperidines (e.g. meperidine), the morphinans (e.g. levorphanol) and 6,7-benzomorphans (e.g. metazocine). Although seemingly structurally diverse, all these compounds either possess a piperidine ring or contain the critical part of its ring structure.
Etorphine, for instance, is a very potent analogue of morphine. On one occasion a team of researchers, working in the 1960s under Professor Bentley of Macfarlan Smith and Co, drank mid-morning tea that had been stirred with a contaminated rod. They were soon laid out. The scientists had unwittingly drunk a drug later developed as etorphine. Etorphine is over 1000 times more powerful than morphine; it is used in dart-guns as Immobilon to subdue elephants and rhinos. Fortunately the scientists recovered.
Morphine was first isolated from opium in 1805 by a German pharmacist, Wilhelm Sertürner. Sertürner described it as the Principium Somniferum. He named it morphium - after Morpheus, the Greek god of dreams. Today morphine is isolated from opium in substantially larger quantities - over 1000 tons per year - although most commercial opium is converted into codeine by methylation. On the illicit market, opium gum is filtered into morphine base and then synthesized into heroin.
Doctors had long hunted for effective ways to administer drugs without ingesting them. Taken orally, opium is liable to cause unpleasant gastric side-effects. The development of the hypodermic syringe in the mid-nineteenth century allowed the injection of pure morphine. Both in Europe and America, members of high society and middle-class professionals alike would jack up daily; poor folk couldn't afford to inject drugs. Morphinism became rampant in the USA after its extensive use by injured soldiers on both sides of the Civil War.
In late nineteenth-century America, opiates were cheap, legal and abundant. In the judgment of one historian, America became "a dope fiend's paradise". Moreover it was believed that injecting morphine wasn't addictive. Quitting habitual opium use can cause malaise, flu-like symptoms, and depression; morphine seemed an excellent cure.
In China, for instance, early twentieth century missionaries handed out anti-opium remedies in such profusion that the pills became known as "Jesus Opium"; their active ingredient was morphine.
Soldiers, missionaries and patent-medicine salesmen were not alone in eulogizing its properties. A leading American medical textbook (1868) revealed that opiates...
"...cause a feeling of delicious ease and comfort, with an elevation of the whole moral and intellectual nature...There is not the same uncontrollable excitement as from alcohol, but an exaltation of our better mental qualities, a warmer glow of benevolence, a disposition to do great things, but nobly and beneficently, a higher devotional spirit, and withal a stronger self-reliance, and consciousness of power.
Nor is this consciousness altogether mistaken. For the intellectual and imaginative faculties are raised to the highest point compatible with individual capacity...Opium seems to make the individual, for a time, a better and greater man...."
Racist stereotypes, rampant xenophobia and lurid images of white slave-traders abounded too. In the 1850s and 1860s, tens of thousands of Chinese had immigrated to the USA to help build the western railroads and work the California mines. Opium-smoking was an integral part of Chinese culture; and its effects offered a merciful relief from dirty and backbreaking work. But the medical tide was turning. Dr Hamilton Wright, newly appointed US opium commissioner, blamed "the Chinese vice" for corrupting the nation's youth....
So the search began for a powerful non-addictive alternative to opium and morphine. In 1874, English pharmacist C.R. Alder Wright had boiled morphine and acetic acid to produce diacetylmorphine, C17H17NO (C2H3O2)2. Diacetylmorphine was synthesized and marketed commercially by the German pharmaceutical giant, Bayer. In 1898, Bayer launched the best-selling drug-brand of all time, Heroin.
"If we could sniff or swallow something that would, for five or six hours each day, abolish our solitude as individuals, atone us with our fellows in a glowing exaltation of affection and make life in all its aspects seem not only worth living, but divinely beautiful and significant, and if this heavenly, world-transfiguring drug were of such a kind that we could wake up next morning with a clear head and an undamaged constitution-then, it seems to me, all our problems (and not merely the one small problem of discovering a novel pleasure) would be wholly solved and earth would become paradise."
ALDOUS HUXLEY
1894 – 1963
Today, by contrast, immense energy is devoted by the authorities into persecuting "illicit" narcotic users. Many drug-"abusers" feel well thanks only to the "non-therapeutic" use of opioids. They are stigmatized, pilloried and criminalized in a futile War Against Drugs.
In the Inquisition against pleasure, victims of medically-sanctioned human-rights abuses - e.g. the hundreds of thousands of drug "offenders" incarcerated in the American gulag - are officially supposed to believe their malaise-ridden drug-naive state was "normal", "natural" and mental healthy.
In the course of our ill-conceived Drug War, vast resources are dissipated by the state-apparatus in an effort to choke off narcotic production and supply. When these efforts are temporarily successful, drug-deprivation makes the habitual opioid user feel ill; [s]he "cold-turkeys" with characteristic dysphoria, irritability, depression and sometimes raw physical pain.
The ill-effects felt from involuntary deprivation of opioids are taken to demonstrate the likely ill-effects of legalized access, a paradox that might be thought labored were its human costs not so tragic.
Even where it is acknowledged that many users have a pre-existing anxiety or depressive disorder in urgent need of relief, those so afflicted are fobbed off with often third-rate psychotropics instead. For a start, the monoamine hypothesis of depression - and the new classes of drug it has spawned (SSRIs, NARIs, SNRIs, NaSSAs, RIMAs etc to complement the dirty old tricyclics and irreversible unselective MAOIs) - is radically incomplete.
A minority of people, admittedly, find such drugs effective. Often taking a licensed antidepressant is better than nothing at all - perhaps in part because of their positive effects on endogenous opioid peptide release.
Yet even in the context of controlled clinical trials with relatively high dosage-regimens and artificially good rates of patient-compliance, it's rare for response-rates to reach more than 70%. Rates of full remission of depressive symptoms are far lower, perhaps 25-30%. Out "in the field", the picture is worse still.
Adverse side-effects are common. Response may take weeks. Withdrawal reactions can be unpleasant.
A recognition of the crucial role of dopamine, and selective dopamine reuptake blockers, in sub-types of depressive mood-disorders might push response- and remission- rates higher. The mesolimbic dopamine system is critical to vitality, motivation, libido and a capacity to anticipate reward. Dopaminergics can also act as analgesics. Yet the FDA stymies the licensing of effective dopamine reuptake-blocking mood-brighteners at home; and applies pressure to deny access to them abroad.
This is because of worries about their (sometimes) faster efficacy - and mild psychostimulant effect - raise the spectre of "abuse-potential"; and proscription, persecution and indiction are favored over consumer education. For Big Brother knows best.
"I'll die young, but it's like kissing God"
Lenny Bruce
"Millions of people suffer needlessly from agonizing pain because physicians have been reluctant to use ‘high-risk’ opioids"
Crain & Shen 2000
"The first thing they told us in medical school is that no one has ever died from pain but plenty of physicians have had their careers destroyed trying to help people who are in pain."
Comment from an emergency room physician requesting anonymity (2001)
Not only do sufferers of chronic pain and narcotic addicts stand to benefit from such harm reduction approaches but, by decreasing drug-associated crimes, a significant area of the true “drug problem” can be directly addressed, thereby benefiting society as a whole.
I know its long but read it, Its very interesting. I think a quote from the band NOFX is do here:
"If God made plants and buds that I find and abuse, then who the **** ARE YOU TO JUDGE ME?"
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