DeadAddict,

This was a problem we had over here during the Blitz of WWII. We used a standard 3.7" AA gun that fired single shells which would explode at a given altitude.

If you hit a bomber, the chances were you got it, its bomb load, and its fuel land on you rather than just the bombs. If you missed the nosecone would come down at near terminal velocity and do damage as well.

You need to totally wipe out a cruise missile, or it will just plough on and damage its target anyway. If you reduce it to very small bits, they won't do much damage even if they do get through?

Cheers