Hmmm,

I believe that part of the problem is that spyware/adware doesn't actualy "do" very much when it arrives. This means that behavioural monitoring does not pick up a lot, and these tools have to rely on pattern files.

I still recommend RegistryProt from DiamondCS, as it will at least warn you that you have a problem, and if you deny the Registry changes the stuff probably won't work.

I use it in conjunction with WinPatrol from BillP Studios and Winsonar. You need to remember to turn Winsonar off to do updates and stuff, and to tell it which new programs you have loaded are "good guys" because it is almost as paranoid as I am