Hi,

As everyone suggests here, it depends more on ones taste. Every program has its pros and cons. i've been using Norton for few years now and really like it. Most of the corporates i've worked with also uses its corporate edition. Norton provides daily signature updates also which is really important.
Now as McAfee is also starting daily signature updates, you may want to give it a try too. What i would suggest is try both of them and evaluate the product features with the list you want. You may evaluate other vendors also if your options are open like http://www.kaspersky.com/

-Joseph