I always found that KDE has far better application integration than Gnome. Maybe I just never figured out Gnome completely, I never used it very much as I never really liked the interface anyway. I found it was difficult to configure and didn't work very well with manual editing of textfiles, although it did load faster than KDE does now.

I've always found the K suite of applciations to integreate with each other seamlessly. Their heavier apps, most notably Konqueror and Koffice, I find lacking in several areas, so I use Mozilla/Firefox and OpenOffice instead. But for everything else, all the little stuff like email, key management, login, multimedia, blah blah blah, I've found the KDE suite to be superior to Gnome.

Just my experience, though.