I never understood why anyone spends hours fixing a computer riddled with spyware/viruses when it takes 30-45min to just re-install everything.
Because then the malware writers win. :?

The only systems that I have not been able to repair were ones that had rootkits installed.

EDIT: Which just lead me to another thought. Currently, there are two variants going around that use rootkits to hide themselves. One is a SwapX variant, which shows as an entry in the trusted zone that will not go away.

The other one is a VX2 variant that alot of people have been working on for awhile with little success. The symptoms are a huge number of pop-ups, and when you delete a file, it bypasses the recycle bin.

If it isn't one of these, once you get it narrowed down to an infector, could I get a sample??