I would try running your scanners in safe mode, you will have a better chance of deleting stuff.

Also, start SpyBot in "advanced mode" and use the tools to check out BHOs, the Hosts file etc.

Good luck


EDIT: you might like to look here: http://www.newbie.org/help/messages/28195.html

EDIT#2:

Appears to open mIRC, also the autoexe contains alot of default username/pass phrases for admin accounts.
That sounds like a member of the rbot/sbot family.............there are about 700 of them! and new ones come out every week.